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The most effective way to get rid of a persistent Bartholin cyst is via surgical drainage. You can see your family doctor, who may do it themselves (if they are experienced with the procedure). Alternatively, they may refer you on to another physician to have the procedure performed.  Most cases of incision and drainage are outpatient procedures done in the doctor's office and only require local anesthetic. An incision (opening) will be made in your cyst, allowing any fluid inside to drain out. A catheter (tube) may be placed into the cyst for up to six weeks following the procedure. This is usually only done for cases of recurrent Bartholin cysts. The purpose of the catheter is to keep the cyst open, so that any further fluid that accumulates can drain out immediately. Keeping the cyst open prevents fluid buildup and, as such, allows the cyst to naturally heal. If your Bartholin cyst appears to be infected, your doctor will prescribe you antibiotics following surgical drainage. It is important to complete the full course of antibiotics, and to not miss taking any of the pills, as missing pills will lessen the effectiveness of the antibiotics.  Also, if you test positive for any STIs, you will receive antibiotics whether or not your cyst is currently infected. The purpose to prevent an infection, as testing positive for STIs heightens your risk that your cyst may subsequently become infected. " If your Bartholin cyst recurs, you can speak to your physician about a procedure called marsupialization. This is when the cyst is surgically drained, and then stitches are placed on either side of the cyst to hold it open following the procedure.  This opening is permanent, and serves to prevent recurrences of the Bartholin cyst. You will likely have a catheter (tube) in for a few days following the surgical procedure; however, after that, the catheter can be removed because the stitches will be strong enough to keep the incision open. If you have a particularly bad cyst, or have had recurrent cysts, one of the "last resort" treatments is to have your Bartholin gland completely removed surgically, or removed via a laser procedure. Both of these are simple procedures that do not require an overnight hospital stay. While many people have asked if there are strategies to prevent (or reduce the risk of) a Bartholin cyst developing in the first place, doctors say that there are no known strategies for prevention. Doctors do recommend that you begin treatment — either home treatment or medical treatment — as quickly as possible once you notice a cyst developing.
Opt for surgical drainage. Take antibiotics. Ask your doctor about "marsupialization. Have your Bartholin gland completely removed. Note that there is no known way to prevent a Bartholin cyst.