Summarize:

Your doctor will be able to decide if Misoprostol is right for you based on your overall health, medical history, and current prescriptions, if any. They will also be able to establish the right dosage of the medication for you. Follow your doctor's instructions for taking Misoprostol exactly and do not change how you take the drug without their approval. Non-prescription drugs can interfere with Misoprostol or exacerbate the symptoms associated with it. Tell your doctor about any over-the-counter drugs you are taking, as well as any  natural supplements or vitamins. If you are already taking Misoprostol and want to start taking a new, non-prescription drug, ask your doctor first. For instance, antacids that contain magnesium can raise your risk for diarrhea, or make it worse. Misoprostol is a strong medication that can cause miscarriage, premature birth, and birth defects if taken when pregnant.To avoid pregnancy, use a reliable form of birth control such as condoms or birth control pills while you are taking Misoprostol. If you are taking Misoprostol and think you might be pregnant, contact your doctor right away. Misoprostol is sometimes used to accelerate a first trimester miscarriage as an alternative to surgical measures. In this scenario, Misoprostol is inserted vaginally or melted under the tongue to soften and relax the cervix. Speak to your doctor about this option, which is still an "off-label" use of the drug. Do not use Misoprostol this way without permission and guidance from your doctor. Some side effects of Misoprostol, such as diarrhea or upset stomach, are mild and common during the first few days on the medication. Other symptoms are more serious and should be disclosed to your doctor right away. Tell your physician if you experience:  abdominal pain convulsions difficulty breathing low blood pressure severe diarrhea fever tremors drowsiness If you exceed your recommended dose of Misoprostol and fear for your health, do not wait to seek help. Call the poison control hotline for your region and and communicate as clearly as you can what drug took, how much you took, and when you took it. You can also contact emergency services for immediate medical care. As a precaution, keep the number for poison control near your telephone in case of emergency.
Take the medication directly as ordered by your doctor. Inform your doctor of any non-prescription drugs that you are taking. Use birth control if you are able to get pregnant while taking Misoprostol. Talk to your doctor about using Misoprostol to accelerate a miscarriage. Contact your doctor about serious side effects. Contact emergency medical services if you suspect an overdose.