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Make sure the blender is plugged in, clean, and in working condition. Clean the blender.
You can pretty much eyeball this one -- if it looks like it's in okay condition, it's probably safe to use.  Be sure to have dry hands, wet hands is a safety hazard with and electric appliance. Remove the blender from the base and wash the two parts separately. Just run the top under warm water with a little soap; the blades are sharp so be careful not to cut yourself.  Never, ever, ever put the base in water! If you get it gunky, take a wet cloth or sponge to it. It's hard to hurt it -- and water (or any other liquid) is really the only way. Be sure to dry the blender completely, you don't want to leave liquid in the blender, its best to air dry upside down.