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Rinse the wound. Wash the wound. Remove any debris. Gently pat dry. Apply an antibiotic cream, especially if the wound was dirty. Cover the wound.
Let cool water run over your skinned knee, or pour it over it. Do this long enough to make sure that the water has flowed over the entire area, and washed away any loose dirt and/or debris. Use antibacterial soap and water to clean around the wound, but try not to get soap in the wound itself, as this can cause irritation. This will help to wash away bacteria and keep away infection. Hydrogen peroxide and iodine were traditionally used to disinfect skin wounds, such as a skinned knee. However, hydrogen peroxide and iodine can actually damage living cells, so medical professionals now advise that you should not apply them to a wound. If anything is stuck in the wound, like dirt, sand, splinters, etc., use tweezers to carefully remove this material. First clean and sterilize the tweezers by rubbing them with a cotton ball or gauze soaked in isopropyl alcohol. Rinse with cool water once the debris is removed. If dirt or other material is lodged so deep in the wound that you cannot get it out, contact a doctor. Once you have rinsed and washed the skinned knee, gently use a clean cloth or towel to dry the area. Patting rather than rubbing it dry will help you avoid unnecessary pain. This can deter infection and help the wound as it heals.  There are numerous types of antibiotic creams and ointments, containing different active ingredients or combinations (bacitracin, neomycin, and polymyxin, for example). Always carefully follow the directions provided with your cream regarding the amount to use and method of application. Some creams have mild analgesics incorporated as pain relief. Some ointments and creams may cause an allergic reaction in some people. If you notice redness, itching, swelling, etc. after using one of these products, stop using it and try another one with a different active ingredient. Make sure to cover your skinned knee with a bandage, to protect it from dirt, infection, and irritation from clothing during the time it needs to heal. You can use an adhesive bandage, or sterile gauze held in place with tape or an elastic band.