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Spend some time looking at different Etsy sellers, especially successful ones, to find your niche in the market. Think about how your artwork can stand out from the crowd. Consider how your work is different and how you can bring a unique perspective to what is already selling on Etsy. For example, you may use the Etsy search bar to look up sellers who are making artwork that is similar to yours. You may notice what types of artwork they sell as well as their price points and their type of clientele. Consider the age group and demographic you want to sell to. Are you trying to make artwork for a younger audience, such as children? Do you want to make artwork for an older audience, such as individuals looking for artwork for their homes or offices? Think about how you can appeal to a specific customer or niche on Etsy. For example, you may try doing animal portraits in cross stitch, rather than paint animal portraits, as these are already popular on Etsy. Or you may create custom abstract art for interiors in interesting materials like spray paint and fabric to stand out. For your artwork to be sold on Etsy, it must be handmade and/or designed by you. If you have a design partner, you must disclose this on your shop. You will also need to disclose every person involved in the making of the item.  You cannot resell items that were not handmade or designed by you. You must be honest and forthcoming in your descriptions of items and in the information you provide about your shop. Appeal to a variety of shoppers by carrying artwork that ranges in price. Try to have artwork that is on the more affordable side and on the more expensive side. Giving variety can open up your shop to a wide range of buyers and encourage your customers return to buy more.  Etsy finds that items $50 USD and under tend to be the most popular. You may use $50 USD as your base price and price your items up or down from there. For example, you may have several pieces that are in the $50-$100 USD range or in the $0-$50 USD range. You may then offer a few larger or more detailed pieces in the $100-$200 USD range. Do not be afraid to offer artwork that is more expensive, as some art buyers are drawn to more expensive work that is original and one of a kind.
Look at what your competitors are selling and making. Pick artwork that is unique and appealing to a specific customer. Make sure your artwork meets Etsy standards. Have artwork at different price points.