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Times when surgery would be needed include any of the following:  uncontrollable and debilitating bowel symptoms such as abdominal pain, diarrhea, and/or constipation excessive bleeding from your digestive tract spread of the infection to other areas of your body. Since the liver is the most common extra-intestinal organ to be infected, it sometimes needs special treatment.   Small liver infections can often be treated with medication alone. In more severe cases, however, your doctor will likely use a needle (with ultrasound guidance) to remove the infection from your liver. Sometimes, severe bowel symptoms (bowel inflammation and/or consistent diarrhea or constipation) are unable to be treated with medications alone. In more serious cases, a portion of damaged colon may need to be surgically removed.  If your colon has been "broken open" (the medical word for this is "perforated"), this will also require surgical repair. Follow the advice of your doctor as to when surgery is needed. " As your body's immune system is busy fighting off the parasite that has led to amebiasis, other bacteria may have the chance to infect you simultaneously. In cases such as these, your doctor may give you more powerful antibiotic treatment to eliminate any additional infections that have occurred at the same time.
Listen to your doctor's advice if he or she recommends surgery. Get your liver treated (via medication or needle drainage) if needed. Have your colon assessed. Be aware of "bacterial superinfection.