Summarize:

Like most pets, lizards require routine veterinary care. Whenever you get a new lizard, bring them to the vet to get a clean bill of health. After this, you should bring your lizard to see the vet once per year.  Your vet will examine your lizard and perform blood tests that can catch health problems before your lizard exhibits symptoms. Lizards will hide any health problems for as long as they can, so preventative care is important for good health. Your vet may recommend quarantining new lizards before introducing them to other lizards in your home. If possible, take your lizard to a vet that specializes in reptiles. The most obvious sign of health problems in uromastyx lizards involves how they are going to the bathroom. If your lizard has diarrhea or constipation (that lasts more than 24 hours), bring your lizard to the vet. Other signs to look for include:  Weight loss. Runny nose, eyes, or mouth. Swollen joints. Discolored skin. Hiding a lot more than usual. A clean cage is crucial to the health and happiness of your lizard. Each day, the substrate should be scooped, food scraps should be removed, and food dishes should be washed. A more thorough cage cleaning should be performed 1-2 times per month.  Follow this procedure:  Move your lizard to another safe location. Wear disposable gloves. Remove everything from the cage. Dispose of sand. Wash water bowls in hot, soapy water. Wash any structures the same way. Wash the inside of the cage. Use hot water and soap to scrub down the cage. You may want to do this outside with a hose. Replace the sand. Once all of the other items are completely dry, return them to the cage. Return your lizard to their cage. A caged that is stocked with rocks, perches, and hollow areas can help keep your lizard entertained. You can also entertain your lizard with food. Hiding their food (so they can forage) and providing live prey (so they can hunt) can help to keep your lizard active and happy.  Hide vegetables in your lizard’s cage to encourage foraging. Crickets are a good choice for live prey. These can be purchased at your local pet store.
Bring your lizard to the vet. Watch for health problems. Clean and maintain the cage. Provide stimulation.