Article: A variety of medications are available to treat neuropathy. Your doctor will focus on managing the medical disorder that's causing your neuropathy which will reduce symptoms and improve the nerve function in your feet. Your doctor may prescribe:  Amitriptyline: This medication, originally used as an antidepressant, effectively treats neuropathic pain. You'll be started on the lowest dose, 25 mg a day. You can gradually increase the dosage to 150 mg per day. Always take the medication before going to bed. This drug should not be prescribed if you have a history of suicide risk.  Pregabalin: This sedative is usually prescribed for pain associated with peripheral neuropathy caused by diabetes. You will start with the lowest possible dose, and increase it as your doctor suggests. The maximum dosage is 50 to 100 mg, taken three times per day by mouth. Maximum dosing may be increased over time to 600mg/day, but dosage over this amount isn't effective.  Duloxetine: This medication is usually prescribed for pain associated with neuropathic pain caused by diabetes. The dosage starts at 60 mg orally. The dosage can be doubled and your doctor will review the treatment after two months. While you can double the dosage, most doses over 60 mg a day are rarely more effective and may actually cause other problems.  Combination therapies: Your doctor may recommend combining several medications such as TCA, venlafaxine, or tramadol. These can provide better results for neuropathy than any single medication alone. Your doctor may prescribe long-acting opiates to treat the pain of your neuropathy. This is usually determined on an individual basis, because side effects include dependence (addiction), tolerance (they become less effective over time), and headaches. Immunosuppressive agents such as cyclophosphamide may also be prescribed to treat a chronic type of neuropathy (dysimmune neuropathy) that may be resistant to other treatments. Depending on the cause of your neuropathy, your doctor may recommend a decompressive surgery. This will release pressure from entrapped nerves which will let them function correctly. Decompressive surgery is often done for carpal tunnel syndrome. But, certain types of hereditary neuropathy that cause issues in the foot and ankle can also benefit from decompressive surgery. Amyloid peripheral neuropathy may be treated by a liver transplant, since this type of neuropathy is caused by metabolic liver problems.
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Take medications prescribed by your doctor. Use opiates as prescribed. Talk with your doctor about surgery.