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One of the primary symptoms that is so common with a malarial infection is a high fever, at least 102°F (38.9°C). It's also one of the first symptoms to appear as early as seven days (although usually between 10 – 15 days) after getting bitten by an infected mosquito. Often the fever comes and goes randomly. This is thought to be related to the malaria parasites transiently spreading into blood from the liver.  There are at least five types of Plasmodium parasites that infect people, although P. falciparum (mainly in Africa) and P. vivax (mainly in Latin America and Asia) are the most common and deadly. The fever and other initial symptoms may be mild and mimic less serious viral infections, such as the common cold and influenza. Usually symptoms don't appear for about two weeks after being bitten. The other primary symptom of malaria is severe shaking chills with intermittent periods of sweating. Again, shaking chills are typical of many other types of infections, but they are usually more pronounced and severe with malaria. They can cause teeth to chatter and even prevent sleep. When they're severe, the shaking can be mistaken for seizures. The chills from malaria are usually not remedied by blanket cover or by wearing warmer clothes.  Although the primary symptoms of malaria typically begin within a few weeks of being bitten by an infected mosquito, some types of malarial parasites can lie dormant in the body for up to a year or more.  Malarial symptoms are caused by the bites from female Anopheles mosquitoes, which inject the parasite into the host's bloodstream. The parasites then migrate to the liver where they lay dormant for a week or two before causing symptoms. Secondary and less specific symptoms of malaria are moderate-to-severe headaches, often combined with mild muscle aches. These secondary symptoms often occur a short while after the above-mentioned primary symptoms as the parasite needs a little more time to proliferate in the liver and spread around the body in the bloodstream. Headaches and muscle aches are also very common with most other infections, as well as from the bites of other insects and spiders.  The bites from female Anopheles mosquitoes are not very noticeable (a small, red, itchy bump), unlike the bites of some other insects and spiders that can cause similar symptoms. The initial headaches of malaria are typically dull in nature (like a tension headache), but as the parasites start to infect and destroy red blood cells, they can become pounding in nature (more like a migraine). The achy pain is usually most noticeable in the leg and back muscles because they are larger, more active and get more of the infected blood. Other non-specific secondary symptoms of malaria are vomiting and diarrhea, multiple times per day. They often occur in combination with each other, which mimics the initial symptoms of food poisoning and other bacterial infections. The main difference is that the vomiting/diarrhea caused by food poisoning fades away within a few days, whereas it can remain for a few weeks with malaria (depending on treatment).  Unlike the explosive and bloody diarrhea of some bacterial infections, particularly Shigella, there's usually no blood or severe cramping with malaria. Once the primary and secondary symptoms become noticeable, the malaria-causing parasites can be seen under a microscope from a drop of infected blood — especially if the specimen is stained with Giemsa stain. If the advancing primary and secondary symptoms don't prompt the infected person to seek medical attention and get treatment (which may not be possible in the developing world), then symptoms begin to appear that signify serious injury / damage to the body. When these advanced symptoms of malaria appear, the risk of health complications and death significantly increase.  Confusion, multiple convulsions, coma and neurological impairment indicate brain swelling and injury. Severe anemia, abnormal bleeding, deep labored breathing and respiratory distress indicate advanced blood infection and lung involvement. Jaundice (yellowish skin and eyes) is evidence of liver damage and dysfunction. Kidney failure Liver failure Shock (very low blood pressure) Enlarged spleen
Watch for a high fever. Take notice of severe shaking chills. Look out for headaches and muscle pains. Be suspicious of vomiting with diarrhea. Recognize the advanced symptoms.