INPUT ARTICLE: Article: Your doctor will probably be the one to suggest lowering your cholesterol and triglycerides if blood tests show your levels are high. Your doctor may recommend combining any number of cholesterol-lowering medications with lifestyle changes. If you're over 20 and haven't been diagnosed with cardiovascular disease, get your cholesterol levels checked every four to six years. If you have been diagnosed with cardiovascular disease, you'll need to have it checked more frequently. Your doctor may prescribe statins which are enzymes (HMG-CoA reductase inhibitors) that effectively lower LDL cholesterol and triglycerides. But, statins also interfere with the formation of other important substances like CoQ10. Ask your doctor about taking a CoQ10 supplement (at least 30 mg/day) while taking the statins.  Side effects of statins include headache, nausea, muscle weakness, muscle pain, and increased risk for diabetes. Statins may interact with prescription medications and herbs. Tell your physician about all medications and herbs you are taking. These can reduce the absorption of fats and reduce the formation of cholesterol in the liver. Bile-acid sequestrants are most effective at lowering LDL but have little effect on HDL-cholesterol or triglycerides. For this reason, your doctor may prescribe them to be used along with other medications. Talk with your doctor if you have gallbladder disease, phenylketonuria, or are taking medications for your thyroid. You should not use bile-acid sequestrants since they may interfere with your medication. Side effects of bile-acid sequestrants include constipation, gas, nausea, and upset stomach. These inhibitors are antibodies that make up a new class of drugs. They work to prevent the formation of LDL cholesterol by the liver. Since this is a relatively new drug, more studies are needed to determine its safety and effectiveness. Side effects are rare, but they include flu-like symptoms, urinary tract infections, muscle pain or spasms and diarrhea. If you're taking statins, your doctor may also prescribe an inhibitor of dietary cholesterol absorption. When combined, they can lower your LDL cholesterol and reduce your triglyceride level to some degree. Cholesterol absorption inhibitors do this safely without disrupting your body's absorption of other nutrients. Side effects include diarrhea, abdominal pain, back and joint pain If statins don't effectively lower your cholesterol and triglycerides, your doctor may prescribe fibrates (like gemfibrozil and fenofibrate). Fibrates primarily reduce triglycerides while increasing HDL cholesterol. You shouldn't take fibrates if you have liver or kidney disease. Side effects include upset stomach, nausea, diarrhea, headaches and muscle aches.

SUMMARY: Talk with your doctor. Take statins. Take bile-acid sequestrants. Take PCSK9 inhibitors to reduce cholesterol. Prevent your body from absorbing cholesterol. Take fibrates.

In one sentence, describe what the following article is about: Most of the usual signs of ripe fruit don't mean much on a pineapple. Sniff the base of the pineapple instead: a strong scent means the pineapple is ripe. If you can barely smell it, it's probably not. Cold pineapples never smell strong, so leave them at room temperature for a while before you try this. A yellow-skinned pineapple is a safer choice than a green one, but this isn't a perfect test. Some pineapples are ripe when completely green. Others have golden or red skins, but are still hard and unpleasant to eat. Pineapples do not ripen properly after they are picked. On your kitchen counter, the pineapple will become softer and juicier, but it will not become sweet. All of a pineapple's sugar comes from the starches in the stem of the plant. Once that source is cut off, the pineapple cannot make more sugar on its own.  Green pineapples will usually change color as well. It's possible that the pineapple will become even more acidic if stored too long. If the pineapple does have a little starch left to convert to sugar, this will be in the base of the fruit. In theory, the sugar might spread better if you keep the pineapple upside down. In practice, the effect is hard to notice, but it might be worth a try.  The skin color also travels from the base upward, although this isn't relevant to the ripeness after picking. If it's difficult to prop up your pineapple, twist off the top and place the exposed end on a damp paper towel. The pineapple should soften within a day or two. Most pineapples will quickly ferment if stored for much longer than this.  If the pineapple was picked unripe, it will still be unpleasant to eat. Keep reading to find out how to improve the taste of an unripe pineapple. If you're not ready to eat the pineapple yet, move it to the fridge for another 2–4 days.
Summary: Smell to test the ripeness. Expect the pineapple to soften, but not sweeten. Prop it upside down (optional). Leave it at room temperature.

INPUT ARTICLE: Article: Doing so will prompt an installation window to appear. It's to the right of the "Folder" address bar in the middle of the pop-up window. Doing so opens a new window. Press Ctrl+V (Windows) or ⌘ Command+V (Mac) to paste in the copied address, then press ↵ Enter. This will ensure that OptiFine installs to your Minecraft directory. It's at the bottom of the OptiFine window. This confirms that OptiFine installed successfully. Click or double-click the Minecraft app icon, which resembles a grassy block of dirt. Doing so brings up the Minecraft launcher window. It's a tab in the upper-right corner of the window. This option is near the top of the list of Minecraft versions. Doing so brings up a page with several text boxes. In the "Name" text box, enter a name for your OptiFine configuration. It's below the "Name" box. Doing so prompts a drop-down menu. This is the drop-down menu option that has "OptiFine" and the current version number of your OptiFine installation in the title. It's a green button at the bottom of the window. In order to select OptiFine as the version of Minecraft to run, do the following:  Click the News tab in the Minecraft launcher window. Click the upward-facing arrow to the right of PLAY. Click your OptiFine configuration's name. Click PLAY.

SUMMARY:
Double-click the OptiFine setup file. Click ⋯. Enter the copied game directory address. Click Install. Click OK when prompted. Open the Minecraft launcher. Click Launch options. Click Add new. Enter a name. Click the "Version" drop-down box. Select the "OptiFine" release. Click Save. Run the OptiFine version of Minecraft.