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These bugs are not the easy to pick off one by one. However, using petroleum jelly makes your glove sticky, which helps pull the beetles off the plant.  These beetles have a yellow body with black stripes or black dots. They measure 0.25 inches (0.64 cm) in length. Drop the beetles into a bucket of water with a couple of spoonfuls of dishwashing liquid. You can use a simple handheld vacuum to suck beetles off the plants. Alternatively, use a reversed leaf blower to suck the beetles out. You can also buy a vacuum specifically made for insects if you're worried about harming the plant, as these are generally less powerful. Vacuum all around the plant, including the underside of leaves. Make sure to empty the vacuum when you're done. Seal the contents in a zip-top bag, and take them to the trash. It may be tempting to take out spiders you see, but they are natural predators for pests like cucumber beetles. Wolf spiders, in particular, eat a large number of these beetles, and the beetles tend to avoid the area if there are wolf spiders around.  Of course, you should still be careful around spiders. By and large, though, if you leave them alone, they'll leave you alone. Wolf spiders are venomous, but they usually just cause some redness and swelling when they bite you. They aren't as harmful to humans as spiders like black widows or brown recluses. Ladybugs take care of a number of garden pests, including cucumber beetles and aphids. In the case of cucumber beetles, the ladybugs eat the pests' eggs, discouraging growth. Start with 1,500 ladybugs for a typical home garden, though you won't harm your garden by releasing too many.  Many organic garden stores sell ladybugs to release in your garden. Place the ladybugs in your refrigerator when you buy them, which will slow them down a little. Spray down your yard thoroughly, and release the ladybugs in the evening. Taking these precautions will help keep them in your yard.
Pick the beetles off by hand using gloves coated in petroleum jelly. Suck up beetles with a vacuum. Leave the spiders in your garden. Introduce a predator like ladybugs.