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Start your reference entry with the title of the regulation. List the CFR title number and year of publication. Identify the page numbers where the regulation appears. Provide a direct URL for the regulation. Use commas instead of periods in footnotes.
Chicago style treats regulations as though they don't have an author, so the first part of your reference entry is the title of the regulation. Type the title in title-case, surrounded by quotation marks. Put a period at the end of the title, inside the quotation marks. Spell out the Code of Federal Regulations in italics, followed by a comma. Type the word "title," followed by the title number. Type a space, then put the year of the code edition in parentheses. Place a colon after the closing parentheses mark. After the colon, provide the page numbers from the print edition of the CFR. Do not use any abbreviations before the numbers, such as "p." Place a period after the last page number digit.  If you accessed the CFR online, go to the Government Printing Office website at gpo.gov to get a PDF of the print version of the regulation. That way, you'll have a page number. If you accessed the CFR online, the last part of your reference entry will be the direct URL or "permalink" for the regulation. Use the PDF available from the GPO, so that you have an online copy of the official print edition of the code. Place a period at the end of the URL. When using a footnote for in-text citation, include all the same information you included in your reference list entry. However, instead of placing periods between the elements, use commas. The only period in a footnote is at the end.