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Apply bodyglide or Vaseline. Dust on a coating of body powder. Wear moisture-wicking fabrics if working out. Wear bandelettes.
Place a small amount of these anti-chafing products onto your fingertips and rub them into any areas of possible chafing. You want to lightly coat the entire area, not heavy enough to go through fabric but not light enough to wear off quickly. The lubricating quality of these products will provide a protective barrier over your skin. Some people also use a thin layer of antiperspirant in the same way. Get a container of body powder and gently dust it over any skin that could chafe. The powder will help to absorb any moisture coming off of your skin. It will also create a barrier between skin-to-skin contact. However, be warned that body powder can stain and come off on clothing. This is another reason to only apply it sparingly. Chafing often occurs while exercising due to the rubbing sensation of skin against skin or fabric. Wearing clothing designed to pull wetness away from the skin will help to eliminate or reduce the severity of chafing. This is also a situation where tighter-fitting clothing may be better than loose cotton. These are lace or light-fabric bands that are held onto your upper thighs with elastic edges. They are meant to prevent chafing on the thigh and can usually be worn throughout the entire day.