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When you have Crohn's disease, you are likely to have severe bouts of diarrhea. To control this symptom, which can be both uncomfortable and bad for your health, you should take anti-diarrheal medication whenever symptoms arise.  Talk to your doctor about what anti-diarrheal medication is right for you. Loperamide is a common over-the-counter medication that is often suggested by doctors. If you are having diarrhea, you'll need to be especially cautious about staying hydrated. Serious or ongoing bouts of diarrhea can cause severe dehydration. Anti-inflammatory drugs are often the first medication doctors will suggest if you have common Crohn's disease symptoms. If these medications don't reduce your symptoms enough, your doctor may then suggest an immune system suppressor, which targets your body's immune response instead of the inflammation caused by the immune response.  Common anti-inflammatory medications prescribed for Crohn's disease include sulfasalazine (Azulfidine), mesalamine (Asacol, Rowasa), and corticosteroids. Common immune system suppressors prescribed to patients with Crohn's disease include azathioprine (Imuran), mercaptopurine (Purinethol), infliximab (Remicade), adalimumab (Humira), certolizumab pegol (Cimzia), methotrexate (Rheumatrex), cyclosporine (Neoral, Sandimmune), and natalizumab (Tysabri). Antibiotics like metronidazole can be helpful in treating the symptoms of Crohn's disease. If other treatments fail, your doctor may prescribe you antibiotics. Talk to your doctor about possible side effects of taking antibiotics, which can include experiencing a metallic taste in your mouth, gastrointestinal issues, and paresthesia. Depending on your symptoms, your doctor may recommend you take other medications.  Your doctor may suggest glucocorticosteroids. These steroids can help reduce inflammation and relieve your symptoms. Once your symptoms are no longer severe, your doctor will likely lower your dosage. Opioids are also a temporary option to help you manage any pain or diarrhea. There are a variety of surgical options available for those with Crohn's disease. If medications have stopped working to control your symptoms, then surgery may be the best option available. Additionally, if you have an acute problem, such as a fistula, fissure, or intestinal obstruction, you may need to have surgery immediately.  Doctors routinely do a resection of the bowels to treat Crohn's disease. This surgery involves removing a piece of the bowel that is diseased and joining back together the healthy portions. It is very common for symptoms to return at some point after surgery. However, it is often necessary to have surgery to treat symptoms even if it is likely that the symptoms will return after several years.
Take anti-diarrheal medication. Take anti-inflammatory or immune system suppressing drugs. Take antibiotics. Talk to your doctor about other medications that are available. Consider surgical treatment.